PRIME MEDICAL CORRIDOR LOCATION * Investment opportunity: 4,551 SF medical/professional office building on a corner lot one block off Hwy 192, positioned between two hospitals — Persan Professional Plaza, 323-327 W. Cypress St, Kissimmee, FL 34741. Zoned T4-O. Future Land Use: MU-V (Mixed-Use – Vine Street Overlay).
Three addressable units (323, 325, 327 W. Cypress) under one roof, each separately metered for electric and water. The building offers approximately 26 individual rooms configured as exam rooms, private offices, and clinic space, plus 6 restrooms, a dedicated waiting room, and multiple reception/lobby areas — built out for medical use throughout its history. New roof (2026). 19 parking spaces including handicap. Building-mounted signage in place.
Flexible leasing: available as a single unit, two combined units, or the entire building. Approximate unit sizes range from ±1,400 – 1,700 SF per individual unit up to the full 4,551 SF for all three combined (unit-by-unit square footage approximate)
Unit configuration: 325 and 327 each have separate exterior entrances and share an interior connecting door, allowing them to be leased/operated together (±2,900 – 3,200 SF combined) or independently. 323 is a standalone unit, currently occupied on a month-to-month lease at a rate below current market — upside on renewal or re-lease. 325 and 327 are currently vacant, offering an owner-user opportunity or lease-up potential at market rents.
The T4-O zoning conditionally permits office and medical/professional office use, and the MU-V future land use designation supports the property’s continued use while offering long-term redevelopment potential under the City’s Vine Street corridor revitalization plan (up to 6.0 FAR / 40 du per acre at the project level, subject to City approval).
Ideal for medical, dental, or professional office use, an investor seeking value-add through lease-up and rent repositioning, or a healthcare group wanting a multi-suite footprint near two hospitals.
Three addressable units (323, 325, 327 W. Cypress) under one roof, each separately metered for electric and water. The building offers approximately 26 individual rooms configured as exam rooms, private offices, and clinic space, plus 6 restrooms, a dedicated waiting room, and multiple reception/lobby areas — built out for medical use throughout its history. New roof (2026). 19 parking spaces including handicap. Building-mounted signage in place.
Flexible leasing: available as a single unit, two combined units, or the entire building. Approximate unit sizes range from ±1,400 – 1,700 SF per individual unit up to the full 4,551 SF for all three combined (unit-by-unit square footage approximate)
Unit configuration: 325 and 327 each have separate exterior entrances and share an interior connecting door, allowing them to be leased/operated together (±2,900 – 3,200 SF combined) or independently. 323 is a standalone unit, currently occupied on a month-to-month lease at a rate below current market — upside on renewal or re-lease. 325 and 327 are currently vacant, offering an owner-user opportunity or lease-up potential at market rents.
The T4-O zoning conditionally permits office and medical/professional office use, and the MU-V future land use designation supports the property’s continued use while offering long-term redevelopment potential under the City’s Vine Street corridor revitalization plan (up to 6.0 FAR / 40 du per acre at the project level, subject to City approval).
Ideal for medical, dental, or professional office use, an investor seeking value-add through lease-up and rent repositioning, or a healthcare group wanting a multi-suite footprint near two hospitals.
Property Details
Price:
$1,500,000
MLS #:
S5155353
Status:
Active
Beds:
0
Baths:
0
Type:
Commercial
Subtype:
Medical Office
Subdivision:
HILLCREST
Neighborhood:
34741kissimmeedowntowneast
Listed Date:
Aug 18, 2026
Finished Sq Ft:
4,551
Total Sq Ft:
4,620
Lot Size:
19,036 sqft / 0.44 acres (approx)
Year Built:
1982
See this Listing
Schools
Interior
Cooling
Central Air
Flooring
Carpet, Ceramic Tile
Heating
Central
Levels
One
Exterior
Building Features
Bathrooms, Reception, Waiting Room
Construction Materials
Brick
Direction Faces
South
Lot Features
Central Business District, Corner Lot, City Lot, Sidewalk
Parking Features
Curb Parking
Roof
Shingle
Security Features
Smoke Detector(s)
Window Features
Rods
Financial
Tax Year
2025
Taxes
$9,116
Map
Community
- Address323 W CYPRESS STREET KISSIMMEE FL
- SubdivisionHILLCREST
- CityKISSIMMEE
- CountyOsceola
- Zip Code34741
Subdivisions in KISSIMMEE
- Association of Poinciana Villages
- BELLALAGO
- BELLAVIDA PH 01
- COMPASS BAY
- EAGLE LAKE PH 1
- EAST PALM RESORT CONDO
- MargaritaVille
- POINCIANA NBRHD 5 NORTH VILL 3
- POINCIANA SUBDIVISION NBRHD 5 NORTH VIL 3
- POINCIANA VLG 2 NBHD 1
- ROLLING OAKS PH 7
- Siesta Lago
- SONOMA RESORT AT TAPESTRY PH 1
- STOREY CREEK PH6
- STOREY LAKE TR K
- SUMMERVILLE RESORT
- VENTURA AT WINDSOR HILLS CONDO PH 1
Market Summary
Current real estate data for Commercial in KISSIMMEE as of Aug 29, 2026
66
Commercial Listed
215
Avg DOM
591
Avg $ / SqFt
$2,398,204
Avg List Price
Property Summary
- Located in the HILLCREST subdivision, 323 W CYPRESS STREET KISSIMMEE FL is a Commercial for sale in KISSIMMEE, FL, 34741. It is listed for $1,500,000 To schedule a showing of MLS#s5155353 at 323 W CYPRESS STREET in KISSIMMEE, FL, contact your InvestPro Properties, Inc. agent at 561-203-7022.
Similar Listings Nearby
Courtesy of EAST PARK REALTY LLC. Disclaimer: All data relating to real estate for sale on this page comes from the Broker Reciprocity (BR) of the Orlando/Tampa – FL. Detailed information about real estate listings held by brokerage firms other than InvestPro Properties, Inc. include the name of the listing broker. Neither the listing company nor InvestPro Properties, Inc. shall be responsible for any typographical errors, misinformation, misprints and shall be held totally harmless. The Broker providing this data believes it to be correct, but advises interested parties to confirm any item before relying on it in a purchase decision. Copyright 2026. Orlando/Tampa – FL. All rights reserved. 323 W CYPRESS STREET
KISSIMMEE, FL
